Leukemia is the cancer of the bone marrow characterized by an abnormal increased in the white blood cells. Thrombocytopenia is a disease characterized by reduced platelet count. Anemia is the lack of red blood cells. So, what is the most common cancer type of plasma?
When it comes from plasma cells, the most common type of cancer is the myeloma. Myeloma cancer, also known as multiple myeloma, plasma cell myeloma, and Kahler’s disease, is a type of hematologic cancer wherein the plasma cells in the bone marrow grow in an uncontrollable manner. When plasma cells undergo genetic mutations and become abnormal, myeloma begins. The abnormal plasma cells which are now called myeloma cells produce monoclonal M proteins, a specific type of antibody, and other proteins. It usually occurs in the most active bone marrows like pelvic bones and ribs. When the number of these abnormal plasma cells is increased, the bones of a person will be weaken and damage which may cause pain and even fractures. The damaged bones cause the release of calcium in the blood which will lead to a hypercalcemia. Normal plasma cells and other white blood cells formation is inhibited by the myeloma cells so the person suffering from the disease will not be able to fight it. Myeloma cells can also cause anemia by preventing the new red blood cells to grow. Since there is an excess antibody proteins and calcium, the filtering and cleaning of the blood by the kidney is also restricted.
Myeloma cancer has different types based in the kind of immunoglobulin that they produce. Immunoglobulin G is the most common type of myeloma which accounts for the 60% of the total number of myeloma patients. In this type of myeloma, the heavy chain of the immunoglobulin is G. Other types if myeloma is Immunoglobulin A, Immunoglobulin D, Immunoglobulin E and Immunoglobulin M.
Myeloma cancer often shows no symptoms during the early stages. However, when the symptoms is present, they are vague and varied greatly since it can affect many organs. Some of the most common symptoms include an elevated blood calcium level, renal failure, anemia, and bone lesions. Other people also shows symptoms like bone pain, extreme tiredness, loss of appetite, increased thirst and urination, nausea, vomiting, urinary tract infection, shingles, shortness of breath, chest pain, numbness especially in the hands and feet, and pneumonia. The diagnosis of this cancer at the early stages is often made accidentally when a person is having blood tests for certain reasons. A doctor may request protein electrophoresis of the blood if the blood test of the person shows a high serum protein, high erythrocyte sedimentation rate and high calcium level. If the result will show the presence of monoclonal protein, he/she is suffering from the disease.
Treatments for the multiple myeloma are available and usually focus on the containment and suppression of the disease. If a person is diagnosed with myeloma cancer, he/she, together with his/her family, should seek more information about the disease and seek for available treatments so it won’ get worse.
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