Mannose or more commonly known as d-mannose is a glucosamine sugar sister and a glucose isomer and has an identical molecular formula with its sibling sugar, glucosamine. Mannose is a simple sugar and is naturally occurring. In its natural condition it is famous to be the most safe of sugars being the only sugar containing no levels of toxicity and is devoid of calories. Too much consumption of this sugar or high intake to the extent of one (1) gram on a 100 ml liquid cannot make you fat and does not get accumulated in the body to any extent appreciable, the reason is that this sugar is easily excreted in the feces and the urine and is not absorbed in the small intestine. D-Mannose is warm water soluble, could not be dissolved in pyridine or in oil, dissolving in water makes a clear solution. Slight solubility in alcohol has been observed in experiments.
D-Mannose side effects are prominent in the treatment of urinary tract infections, D-Mannose being a simple sugar appears as a safe treatment of UTI’s, the property of d-mannose being 8x slower to be absorb compared to glucose. Its non-conversion to glycogen nor stored in the liver when ingested makes this an ideal urinary tract infection treatment. It goes instantly towards the bloodstream from the gastro intestinal tract, thereby making d-mannose kidney filtered going towards the bladder.
While d-mannose side effects to UTI is a viable treatment alternative, ingestion of d-mannose produces a burnt sugar, bitter aftertaste. Compared to sucrose it is less than a quarter in its sweetness. An ‘icing sugar’ is a dominant sensation at the mouth’s roof if d-mannose is ingested in its dry form, prevalent if adulterated with other sugars. As a tea or fruit juice sweetener D-mannose is wanting in aftertaste. D-mannose cannot be detected by taste if dissolved in water in normal level dosage of 1.75 to 3.5 grams. Taking as a sweetener for cranberry, coffee or even green tea is not advised.
D-mannose side effects of UTI is easily ameliorated with the use of D-mannose treatment and has been shown in tests to be ten times effective than cranberries in eliminating the E. coli bacteria from the walls of the bladder within a window period of 24-48 hours after ingestion.
Since d-mannose has anti-bacterial properties, unequalled in treating UTI, vaccines have been developed in an attempt to imitate the effects of d-mannose ingestion in preventing adhesion of bacterial epithelium, in particular the E.coli and other bacteria of the gram negative kind. Nothing comes close in the developmental stage, in the mannose effect of bacterial adhesion prevention, reducing swelling as among the results. D-mannose does not eradicate bacteria as its inherent property, but makes it difficult for the bacteria to agglomerate allowing the body to excrete the bacteria pathogens through the routes of the urine and feces. As for the friendly bacteria in the body, they are left unharmed and untouched by d-mannose for they are lacking in the ‘pili’ which a bacteria of pathogenic nature requires for adhesion, making it difficult for mannose to attach and make manifest the d-mannose side effects of UTI.
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