Progesterone Cream: What You Should Know

Progesterone cream is used in women to ease menopausal symptoms. One of the hormones found in a women’s body is progesterone. It is a steroid hormone made up of corpus luteum of the ovary at ovulation. This hormone is also secreted by the adrenal glands in smaller amounts. The precursor of this hormone is known as the pregnenolene.

This progesterone hormone is needed in women, in hormone replacement therapy for menopausal women for many reasons. The most important role of this hormone is to oppose the effects of estrogen hormone. In the absence of the progesterone hormone there is a higher risk of developing reproductive cancer and breast cancer in women.

The hallmark symptoms of estrogen dominance can be easily recognized by menopausal women and in women suffering from the pre-menstrual syndrome.

The main symptoms are as following:

-mood swings

-feeling of bloating



-tender breasts

-weight gain


-uterine fibroids


Estrogen hormone dominance can also cause cancer of the breast, ovary and uterus

Every woman in about 15 years, have anovulatory cycles. Due to this enough estrogen is produced in the body to start menstruation. In this stage no progesterone is produced and there is a stage of estrogen dominance that exists in women. By using the progesterone cream during the anovulatory months can help to prevent symptoms of the pre-menstrual syndrome.

Before using the progesterone cream, one should familiarize themselves about perimenopause. It is important to choose the right progesterone cream as this cream is available at local health stores or online. A doctor should be consulted before using this cream as he will guide you in picking up the right progesterone cream and also will instruct you on its correct usage. Before buying this cream one should make sure that the cream contains only natural ingredients and no synthetic ingredients are used in it. Also one should be aware of how many milligrams of progesterone are contained per ounce of cream. Some creams contain helpful ingredients like the wild yam and ginseng. After the right cream is chosen only 1/16 of teaspoon should be applied twice a day. The cream should be used for a month and the dose should be modified accordingly under the doctor’s advice.

The usual dose recommended for premenopausal women is 15-24mg/day for 14 days before the expected menses. For postmenopausal women the usual dose that works is 15mg/day for 25 days of the month.

As progesterone is fat soluble it is easily absorbed from the skin. Progesterone is absorbed into the capillary blood by the subcutaneous fat. The best absorption skin sites are: face, neck, inner arms, breasts, palms of the hands and the chest.

The side effects seen by the progesterone cream application are usually temporary. They are as follows:

-increased mood swings

-increased hot flashes

-increased headache

-increased menstrual cramping

-weight gain specially in the hip and the belly area

-decreased sex drive

-increased hair thinning

Normally the progesterone hormone causes increased sleepiness. This effect is mainly seen when progesterone pills are taken orally as it gets metabolized in the liver. However when the progesterone cream is applied it gets absorbed directly into the skin, bypasses the liver and gets absorbed into the capillary blood and hence does not cause sleepiness.

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